Hi! I'm Joynal
Research Interests
My main research interest is on bioorganic chemistry utilizing protein nano cage architectures towards biomedical applications.
I am primarily involved in (I) synthesizing organic molecules of particular interest; (2) synthesizing new linker molecules for bioconjugation with proteins and peptides for loading therapeutic agents (III) Surface modification of protein nano cage architectures and subsequent development towards targeted imaging and therapeutic delivery.
Education
2002 Ph.D., Organic/Organometallic Chemistry, The University of Montana, Missoula
Thesis Title: “ Reactivity of Electron Deficient Benzoheterocycle
Triosmium Clusters” Advisor: Professor Edward Rosenberg
1991 M. Sc., Organic Chemistry, Jahangirnagar University, Bangladesh
Thesis Title: “ An Alternative Synthesis of Adrenalol”
Advisor: Professor Abdul Hai
1988 B. Sc., Chemistry, Jahangirnagar University, Bangladesh
Publications
1. Supramolecular Protein Cage Composite MR Contrast Agents with Extremely Efficient Relaxivity Properties; Lars O. Liepold, Md Joynal Abedin, Emily D. Buckhouse, Joseph A. Frank, Mark J Young, Trevor Douglas; Nano Letters, 2009, ASAP;
2. “Synthesis of a Cross-Linked Branched Polymer network In the Interior of a Protein Cage.” ; Md Joynal Abedin, Lars Liepold, Peter Suci, Mark Young, Trevor Douglas; J. Am. Chem. Soc. (2009) , 131(12), 4346-4354
3. “Experimental and Computational Studies of Nucleophilic Attack, Tautomerization, and Hydride Migration in Benzoheterocycle Triosmium Clusters.” Joynal Abedin and Edward Rosenberg, Djamaladdin G. Musaev,* Taraneh Nowroozi-Isfahani, and Keiji Morokuma, Kenneth I. Hardcastle; Organometallics, 2006, 25 (1), 203 -213.
4. “Reactions of Electron-Deficient Benzoheterocycle Triosmium Complexes with Lithium Isobutyronitrile; Edward Rosenberg, Shariff E. Kabir, Md. Joynal Abedin. Hardcastle, Kenneth I; Organometallics, 2004, 23(16), 3982-3989
5. Kabir, Sharif E.; Malik, K.M. Abdul; Mondal, S. Himadri; Mottalib, M. Abdul; Abedin, M. Joynal; Rosenberg, Edward; “The Reaction of Os3(CO)9(m3- H2C7H3(2-CH3)NS)( m-H) with Diazomethane. The First Example of a Trimetallic Cluster Containing a m-Methylidyne and a s-Methyl”, Organometallics (2002), 21(13), 2593-2595.
6. Edward Rosenberg, Md. Joynal Abedin, Dalia Rokhsana, Alessandra Viale, walter Dastru, Roberto Gobetto, Luciano Milone, kenneth hardcastle, “ Ligand Dependent Structural Changes in the Acid – Base Chemistry of Electron deficient Benzoheterocycle Triosmium Clusters,” Inorganica Chimica Acta (2002), 334, 343-354.
7. Islam, Rafiqul; Abedin, M. Joynal; Khayer, Khurshida; Islam, M. Rabiul. “Synthesis of 5-Spiro(5’- Methylisatin)-4-Acetyl-2-(Acetylamino) -D2-1,3,4-Thiadiazoline and 5-Spiro(5’-Methylisatin)-4-Acetyl-2-(5’- Methylisatin-3’-Hydrazino)-D2-1,3,4-Thiadiazoline”. Indian J. Chem., Sect. B: Org Chem. Incl. Med. Chem. (2001), 40B(3), 240-242
8. Abedin, S. M. Tareque; Hardcastle, Kenneth I.; Kabir, Sharif E.; Malik, K.M. Abdul; Mottalib, M. Abdul; Rosenberg, Edward; Abedin, M. Joynal “Carboxylation of a m3-Diazo Methylidyne Triosmium Cluster”. Organometallics (2000), 19(26), 5623-5627.
9. Rosenberg, E.; Abedin, M. J.; Rokhsana, D.; Osella, D.; Milone, L.; Nervi, C.; Fiedler, J. “The Electrochemical Behavior of Electron Deficient Benzoheterocycle Triosmium Clusters”. Inorg. Chim. Acta (2000), 300-302, 769-777.
10. Md. J. Abedin, B. Bergman, R. Holmquist, R. Smith, E. Rosenberg, J. Ciurash, K. Hardcastle, J. Roe, V. Vazquez, C. Roe, S. Kabir, B. Roy, S. Alam, K.A. Azam, “Electron Deficient Bonding of Benzoheterocycles to Triosmium Clusters: Synthesis and Applications to Organic Chemistry,” Coord. Chem. Rev. (1999) 190-192, 975.
11. Islam, Md. Rabiul; Abedin, Md. Joynal; Md. Mamun; Duddeck Helmut,“Synthesis of
1-Methyl-bisDioxopyrrolino[2’,3’:2,3:2”,3”: 6.5]Benzene and its Heterocycles via Thiocarbohydrazone, Thiosemicarbazone,” J. Bangladesh Chem. Soc.(1998) 11(1 & 2), 71-78.
12. Rahim, M. Abdur; Abedin, M. Joynal; Islam M. Rabiul; “Methylation of 9- Bromo- and 7- Chloro- Indolo[2,3-b] Quinoxalines (indophenazines). Jahangirnagar University Journal of Science, Bangladesh (1995), vol 19, 23-29.
